Andy Xu
Davis, California, United States
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With over 20 years of industry experience and a decade of proven leadership, I specialize…
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2K followers
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Andy Xu reposted thisAndy Xu reposted thisExcited to be at BPI2026 next week in Boston. Hope to make some new connections and meet up with old colleagues! #BPI2026
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Andy Xu reposted thisAndy Xu reposted thisI am looking for people to build with at the AI Tinkerers "Agents, Everywhere" hackathon in San Francisco this Saturday, Sept 12. One, two or three! An agent will hand you thirty thousand lines in one go. Splitting that into forty pull requests only helps if they're the right forty, each one coherent enough that a reviewer can hold it in their head and say yes. The sequencing has to be good. That's a planning problem, and it has to be solved before any code is written. We're building one command that turns an existing repository into one agents can work in under review. So bring a repo you own. Not code, a repo. You leave with agent workflows running in your own project, and we find out whether this survives contact with a codebase that isn't ours. Useful if you know your way around GitHub Actions, or you've tried to get an agent to do real work in a real codebase and watched review become the bottleneck. If you have worked with copier that would be excellent too. The SF room is small. A handful of teams, not a hall of three hundred. A working day, not a keynote. Attendance is by application and there's still room: https://lnkd.in/gvd-b5fR Apply, then add yourself to the team called 1000lines. No need to check with me first. Questions welcome in the comments. What we're building: https://lnkd.in/gnE9GWqD A repo already wired for it: https://lnkd.in/gVp-9AWnGitHub - Orchestra-Bio/symphony-example: A sanitized copy of our configuration to use symphony server.GitHub - Orchestra-Bio/symphony-example: A sanitized copy of our configuration to use symphony server.
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Andy Xu reposted thisAndy Xu reposted thisMany biotechs today don't have their own labs. Their team sits in an office orchestrating the work of CROs, CDMOs, and other external partners. But what you gain in speed and cost you can lose in control. Every study running at a CRO is a complex project that has to be monitored and managed by someone. The real state of each one is scattered across SOWs, emails, meeting notes, reports, invoices, and change orders. Across many concurrent studies that becomes a full time job most teams are not staffed to do well. Until recently, this context rich, reasoning heavy work could only be done by a person. Today, AI agents can do it on your behalf. In our latest post, we show how Orchestra's agents can manage CRO engagements from contract to delivery. https://lnkd.in/g3uWmpPW
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Andy Xu reposted thisAndy Xu reposted thisAI scientists have taken the industry by storm, already delivering productivity gains in discovery. But their lasting value will hinge on predictive validity. In the third piece of our Agents for R&D series, Soleil Wizman and I map out the full stack of AI driven drug discovery https://lnkd.in/eCZ5FybQ
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Andy Xu reposted thisAndy Xu reposted thisFor the second piece in our Agents for R&D series, Soleil Wizman and I go deep on R&D strategy: the bets made years before a molecule reaches a patient. Read to learn how competitive intelligence, business development, and indication selection, are being rebuilt around AI. https://lnkd.in/e2jNvARM
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Andy Xu reposted thisAndy Xu reposted thisIf you're attending the 25th Annual BioIT World conference in Boston, stop by 708 and say hello to the Orchestra team👋🏼
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Andy Xu reposted thisAndy Xu reposted this𝐎𝐫𝐜𝐡𝐞𝐬𝐭𝐫𝐚: It was a great event this afternoon at Pillar VC in Boston highlighting how agentic AI is changing the way R&D and drug development are done at all of their stages. Thank you to Madelyn Heart and Pillar for hosting, and to all of the great speakers! If you'd like to learn more about how agents can help you manage the business of science, reach out to Ashoka Rajendra at Orchestra.
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Andy Xu reposted thisAndy Xu reposted thisTwo days until founders and practitioners showcase how agentic AI takes on real work in drug development. Hosted by Orchestra and Pillar VC on May 14th, we look forward to hearing from: Stuart Ince, VP of Program Leadership & Operations,Accent Therapeutics, Inc. Daniel Price, VP of Computational Biology, Nimbus Therapeutics Chung-Han Lee, MD/PhD, VP of Clinical Development, Pheon Therapeutics Alec Nielsen, Co-founter & CEO, Asimov Adam Kraut, Director of Research Informatics & Data Architecture, Metaphore Biotechnologies Stacy Chin , Co-Founder, Scout Ashoka Rajendra, CEO, Orchestra Whether you're a biotech founder, operator, or AI-curious, come join us for demos, dinner, drinks, and open networking. Space courtesy of Pillar VC. A handful of spots left so RSVP here: https://luma.com/ufne6ylk
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Andy Xu reposted thisAndy Xu reposted thisAs agentic AI starts taking on real work in drug development, Orchestra + Pillar VC are bringing together founders and practitioners in Boston on May 14th to show what that actually looks like. Demoing live: - Dan Price, VP of Computational Biology @ Nimbus Therapeutics - Stuart Ince, VP of Program Leadership & Operations @ Accent Therapeutics - Jon Lee, VP of Clinical Development @ Pheon Therapeutics - Alec Nielsen, Co-founder & CEO, Asimov - Adam Kraut, Director of Research Informatics & Data Architecture - Stacy Chin, Co-Founder, Scoutgrants.ai Dinner, drinks, and open networking included. Space courtesy of Pillar VC. Only a few spots left — if you're a biotech founder, operator, or AI-curious and want a concrete sense of what's possible, come join us. RSVP: https://luma.com/ufne6ylk
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Andy Xu reacted on thisAndy Xu reacted on this🚀 Your agents are telling you what's wrong. Now you can actually hear them. I'm proud to share that my team has just launched Agent Insights in Microsoft Foundry, now in public preview! 🎉 Something my team has been heads-down on for months is finally out. We built it for a problem we kept seeing. Teams would ship an agent, turn on tracing, and end up with thousands of traces and no good way to answer basic questions. What keeps breaking? Is it getting worse with the new version? What should we fix first? Reading traces one at a time works for debugging a single run. It doesn't scale beyond that. Agent Insights reads your agent's production traces for you and groups the patterns that keep coming up. That could be tool calls failing, latency creeping up, hallucinations, token costs climbing, and so on. Each insight comes with: 🔍 A category: tool call failures, latency, hallucinations, cost and tokens, reliability errors, output quality, context and memory, or security and risk ⚠️ A severity (High, Medium or Low), so you know where to start 🧵 Example traces with summaries, durations and token counts 🧬 The agent versions affected, to help you catch regressions 💡 A likely cause and suggested actions for what to do next Trying it is quick. Open your agent in the Foundry portal, go to the Insights tab, pick a judge model and click "Run scan now." If you'd rather use code, the Python SDK lets you run scans on demand or on a schedule. MCP tools and skills are also supported. No matter you're running agents on Foundry or somwehere else, please give it a spin and let me know what it finds, good or bad. We're reading every piece of feedback. Blog: https://lnkd.in/gd7G_-hB Docs: https://lnkd.in/gaA6xvGw #MicrosoftFoundry #AIAgents #ObservabilityInsights in Microsoft Foundry: Turn Agent Traces into ActionInsights in Microsoft Foundry: Turn Agent Traces into Action
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Andy Xu liked thisAndy Xu liked thisExcited to be at BPI2026 next week in Boston. Hope to make some new connections and meet up with old colleagues! #BPI2026
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Andy Xu reacted on thisAndy Xu reacted on thisI wanted to take a moment during my first week at KPMG to thank everyone who reached out or commented with congratulations. I genuinely appreciate it. This opportunity didn’t come easy. It took 13 months of navigating ATS systems, rewriting countless resumes, asking for referrals, and being a final candidate a few times. In a market where so many talented, experienced people are struggling to find work, I feel extremely fortunate to be here. Thank you to everyone I leaned on during the process — every referral, every conversation, every bit of encouragement mattered. And if you’re still in the thick of it, I’m here to help however I can, even if it’s just a conversation to ease some of the anxiety. LinkedIn has been a tough place to scroll these last few years, but supporting each other makes a difference. —gq
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Andy Xu liked thisAndy Xu liked thisWe are hiring two tenure-track Assistant Professors in Biomedical AI at Virginia Commonwealth University! Join us in the Department of Cellular, Molecular and Genetic Medicine (VCU School of Medicine) to help build and shape our new Division of BioAI. We are looking for colleagues developing cutting-edge AI and computational methods to decode biology and disease. Areas of high interest include: • Biomedical Foundation Models: Virtual cells, virtual tissues, and digital twins • Oncology & Therapeutics: AI for cancer biology, tumor microenvironment modeling, and drug discovery • Mechanistic AI: Causal, perturbational, and interpretable AI for target discovery and disease mechanisms (Researchers working across other transformative directions in biomedical and molecular AI are strongly encouraged to apply!) Why join us? You will build an independent research program with rich collaborative ties across the VCU School of Medicine, Massey Comprehensive Cancer Center, and the Wright Center for Clinical and Translational Research. 🗓 Timeline: Review of applications begins October 1, 2026, and will continue until positions are filled. 🔗 Apply here: https://lnkd.in/ewvvqA-X Please share with colleagues, postdocs, and trainees who would be a great fit. Feel free to reach out directly or send a message if you want to connect! #BiomedicalAI #AIforScience #ComputationalBiology #MachineLearning #CancerResearch #FoundationModels #AcademicJobs #FacultyHiring #VCUAssistant Professor - Division of Biomedical AI, Cellular, Molecular and Genetic Medicine - MCV Main Campus, Virginia, United StatesAssistant Professor - Division of Biomedical AI, Cellular, Molecular and Genetic Medicine - MCV Main Campus, Virginia, United States
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Andy Xu liked thisAndy Xu liked thisI’m currently open to new opportunities as a Frontend or Full-Stack Developer 🚀 I’m especially interested in Senior-level or more advanced roles where I can take ownership, solve interesting problems, and contribute to both the technical direction and the product. If you know of a team that’s hiring or think I could be a good fit, feel free to reach out!
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Andy Xu liked thisAndy Xu liked thisHiring GenAI framework engineer. Send me resume if you are passionate about RL post training and have relevant experiences: https://lnkd.in/gRb9BGmF
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Andy Xu reacted on thisAndy Xu reacted on thisProf. Bowen Zhou, from the Dept. of Electronic Engineering and Director and Chief Scientist of Shanghai AI Laboratory, was named to the 2026 TIME 100 AI “Thinkers” list as the category’s only scholar from China. His work brings a vital perspective from China to global #AI safety, advancing understanding of intelligence and its responsible real-world deployment.
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Jeffrey DeCoux
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Vijay Bendigeri, Ph.D., excellent post. The truth is, this new multi-trillion-dollar Industry requires INTELLIGENT INFRASTRUCTURE to address supply chain logistics, optimization, orchestration, reduced emissions, Vision Zero, and enabling Autonomy 2.0. Exceptional work has advanced the vehicle with sensors, software, computing, AI algorithms, and safety features. It is far more than the vehicle. Exciting times for our nation, Building Our Next Golden Age. The national buildout of Intelligent Infrastructure Economic Zones will revitalize infrastructure in the United States. Supporting NextG for DoD and Civil, FAA NextGen, Intelligent Transportation, Golden Dome, resilient grids, precise positioning, and autonomous systems. ODC AI-RAN is the convergence of AI and the physical world. Autonomy Institute https://lnkd.in/giehikzr
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Shehab Amin
LakeSail • 2K followers
This is interesting: the smallest #Sail instance on ClickBench using c6a.2xlarge (8 vCPUs and 16 GiB of memory) outperforms every #Spark and Spark accelerator configuration across all instance sizes. The best-performing Spark setup is the Comet Accelerator on c7a.metal-48xl (192 vCPUs and 384 GiB of memory). It’s wild that Sail, running on just 8 vCPUs and 16 GiB, still significantly outperforms an accelerated Spark workload running on 192 vCPUs and 384 GiB. Notably, both Sail and Comet are powered by #DataFusion. Benchmark: https://lnkd.in/gSMjxrtR Sail: https://lnkd.in/gQiakuU6
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Arun Seetharaman
Context Science • 2K followers
TL;DR: The best way to beat a viral open-source project? Build the same thing "better". And ship it inside the product people already pay for. Welcome to Claude Code Channels. That's exactly what Anthropic just did. This week, Anthropic launched Claude Code Channels: a native way to connect Claude Code directly to Telegram and Discord. You assign it a task, step away, and get a message when it's done. Your phone becomes a remote control for your entire dev environment. This is a direct answer to OpenClaw, the open-source agent that became the fastest-growing project in GitHub history by offering this exact workflow. OpenClaw was compelling. It was also a security minefield: a CVSS 8.8 vulnerability, 50,000+ exposed instances, and a community skills registry where ~12% of plugins turned out to be malicious. Anthropic watched all of this unfold and responded not with a legal strategy (well, also that), but with a product strategy. The deeper shift here isn't about Discord bots or Telegram integrations. It's about a fundamental change in how we work with AI: • From synchronous (ask → wait → answer) to asynchronous (assign → go live your life → receive result) • From AI as a tool, you visit to AI as a collaborator that runs in the background • From open-source workarounds to enterprise-grade defaults Developers have been hacking together "always-on AI" workflows for months because the demand was real. Anthropic just made it native, sandboxed, and safe. The question for every team building on AI right now: are you still designing for synchronous interaction, or are you building for the async-agent world that's already here? #AI #DeveloperTools #ClaudeCode #ArtificialIntelligence #SoftwareDevelopment
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Devesh Raj
Fidelity Investments • 13K followers
Open AI’s Codex 5.3 and Claude Opus 4.6 (released on Feb 5th) aren’t just incremental upgrades, they signal a structural shift. What’s emerging is not better content generation. It’s increasingly dependable multi-step reasoning inside real workflows. And that is a big jump. When models can plan, execute, and maintain context with growing stability, AI stops being a tool you use. It becomes a system you design around! #AI #GenerativeAI #LLMs
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Mike Tamir, PhD
Tubi • 54K followers
MiniCPM5-2B is a dense 2B open-source SOTA model optimized for on-device deployment, local coding agents, and agentic workflows, featuring a 131k context length and accompanying high-quality training datasets. https://lnkd.in/gUes558T #MachineLearning #AI #LLM #DeepLearning #AgenticAI
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Charles Barker
Aptia Group • 2K followers
One nice tip for your AI workflows....NotebookLM has a great capability for turning a pile of messy unstructured information from documents or websites into a neat "data table", ie structured, organized data that is easily ingestible in AI orchestration with high quality and low-latency/overhead. This has come in handy for me more than once so I thought I'd share in case it helps someone else who's trying to organize input data quickly for their AI features.
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Kirsten Lum
Schemantic.io • 3K followers
So if semantic objects aren't schema objects like tables and columns, what are they? In short, they are units that link a concept in the real world to data in the database when those concepts need to be modeled as logic rather than as a column. That's right -- semantic layers are only required because database schemas are rigid, slow-moving, unversioned and unversionable objects. That's why people who only work on toy datasets like taxis and iris can't understand why a semantic layer would be necessary. IT ISN'T...if your data model is perfect. But in the real world, the best planned data model gets out of data almost immediately. Even if one source system manages to reflect reality perfectly, introducing a new data source by definition introduces a conflicting data model. If you want to query across them you either have to create a third harmonized data model and perfectly maintain it...or create a semantic layer that abstracts the objects they share into a parallel plane. And in that plane, we can be flexible, move fast, use versioning...all without weeks of ELT writing. So, finally, what is in this plane? We haven't normed on this as an industry, but I have an opinionated view, which is the view we've built http://schemantic.io around. The core objects are: - Entities - Events - Attributes ## Entities This is the foundation of the semantic layer. Each one of these represents a distinct noun in reality -- people, places, things, ideas. Fundamentally, these are ID columns. Everything else "hangs" on these objects. ## Events If entities roughly represent space, events represent time. They define how and when entities interact. They are fundamentally dates, and their names explain what the interaction is. Because of this principle, events "link" entities together. ## Attributes Virtually everything else in a database is an attribute. These contain the characteristics of an entity. Fundamentally, these values can be integers, strings, booleans. They can be categories, scalars, anything at all. They just need to be "bound" to an entity. Each of these objects has its own logic, written in SQL, so that they can composed by humans and machines into the infinitely complex queries we all need to write. And like all objects (both schema and semantic), they have context. But that is a topic for my next thread. If you want to see how a semantic layer can accelerate your analytics and AI readiness, request a demo here: https://lnkd.in/gXyjiq3e
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Mike Vitale
Wowza • 2K followers
If your streaming workflow needs precise business logic, custom modules are the answer. This Thursday, Ian Zenoni and I are digging into how to extend Wowza Streaming Engine through scalable, real-world implementations. We’ll cover when modules make sense, walk through a practical example of custom metadata injection, and share hard-earned tips on testing, debugging, and running modules in production. If you’ve ever said “I just need Engine to do one more thing,” this session is for you. I will, of course, be dressed in my finest sports coat and strongly encourage audience participation. Bring your questions.
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