The Python Database API (DB-API) defines a standard interface for Python database access modules. It's documented in PEP 249. Nearly all Python database modules such as sqlite3, psycopg and mysql-python conform to this interface.
Tutorials that explain how to work with modules that conform to this interface can be found here and here.
SQLAlchemy is a commonly used database toolkit. Unlike many database libraries it not only provides an ORM layer but also a generalized API for writing database-agnostic code without SQL.
pip install sqlalchemy
The Django ORM is the interface used by Django to provide database access.
It's based on the idea of models, an abstraction that makes it easier to manipulate data in Python.