Initialize() crash from .NET Framework application #2205

Environment

• Pythonnet version: 3.0.1
• Python version: 3.10
• Operating System: windows 11/10
• .NET Runtime: NET Framework 4.6.1

Details

I am trying to call Python code from .NET Framework app but on some machines PythonEngine.Initialize() crashes.

Runtime.PythonDLL = "C:\\Python\\Python310\\python310.dll";
PythonEngine.Initialize();

Exception:

System.TypeInitializationException: 'The type initializer for 'Delegates' threw an exception.'

There are two inner exceptions:

DllNotFoundException: Could not load C:\Python\Python310\python310.dll.
Win32Exception: %1 is not a valid Win32 application

The path is correct and the dll exists.