diff --git a/Lib/test/test_code.py b/Lib/test/test_code.py
index 631e5fd2499b13e..90bf49df65151d2 100644
--- a/Lib/test/test_code.py
+++ b/Lib/test/test_code.py
@@ -1606,6 +1606,12 @@ def test_free_called(self):
             gc_collect()  # For free-threaded build
             self.assertEqual(LAST_FREED, 100)
 
+            f = self.get_func()
+            SetExtra(f.__code__, FREE_INDEX, None)
+            del f
+            gc_collect()
+            self.assertEqual(LAST_FREED, 100)
+
         def test_get_set(self):
             # Test basic get/set round tripping.
             f = self.get_func()
diff --git a/Misc/NEWS.d/next/C_API/2026-10-19-20-38-17.gh-issue-159739.b7c351.rst b/Misc/NEWS.d/next/C_API/2026-10-19-20-38-17.gh-issue-159739.b7c351.rst
new file mode 100644
index 000000000000000..b123ce7022ca04b
--- /dev/null
+++ b/Misc/NEWS.d/next/C_API/2026-10-19-20-38-17.gh-issue-159739.b7c351.rst
@@ -0,0 +1,3 @@
+Stop invoking code-extra cleanup callbacks registered with
+:c:func:`PyUnstable_Eval_RequestCodeExtraIndex` for ``NULL`` data, as
+documented.
diff --git a/Objects/codeobject.c b/Objects/codeobject.c
index 724243d2b8cfae1..3a86b9b08fb19ad 100644
--- a/Objects/codeobject.c
+++ b/Objects/codeobject.c
@@ -2415,7 +2415,7 @@ code_dealloc(PyObject *self)
         for (Py_ssize_t i = 0; i < co_extra->ce_size; i++) {
             freefunc free_extra = interp->co_extra_freefuncs[i];
 
-            if (free_extra != NULL) {
+            if (free_extra != NULL && co_extra->ce_extras[i] != NULL) {
                 free_extra(co_extra->ce_extras[i]);
             }
         }