diff --git a/prometheus_client/openmetrics/parser.py b/prometheus_client/openmetrics/parser.py
index 0c5c9c41..00180de5 100644
--- a/prometheus_client/openmetrics/parser.py
+++ b/prometheus_client/openmetrics/parser.py
@@ -307,7 +307,7 @@ def _parse_nh_sample(text, suffixes):
 
 def _parse_nh_struct(text):
     pattern = r'(\w+):\s*([^,}]+)'
-    re_spans = re.compile(r'(positive_spans|negative_spans):\[(\d+:\d+(,\d+:\d+)*)\]')
+    re_spans = re.compile(r'(positive_spans|negative_spans):\[(-?\d+:\d+(,-?\d+:\d+)*)\]')
     re_deltas = re.compile(r'(positive_deltas|negative_deltas):\[(-?\d+(?:,-?\d+)*)\]')
 
     items = dict(re.findall(pattern, text))
diff --git a/tests/openmetrics/test_parser.py b/tests/openmetrics/test_parser.py
index 79a2158c..c14f90ef 100644
--- a/tests/openmetrics/test_parser.py
+++ b/tests/openmetrics/test_parser.py
@@ -266,6 +266,18 @@ def test_native_histogram_three_pos_spans_no_neg_spans_or_deltas(self):
         hfm.add_sample("nhsp", None, None, None, None, NativeHistogram(4, 6, 3, 2.938735877055719e-39, 1, (BucketSpan(0, 1), BucketSpan(7, 1), BucketSpan(4, 1)), None, (1, 0, 0), None))
         self.assertEqual([hfm], families)
 
+    def test_native_histogram_negative_span_offsets(self):
+        families = text_string_to_metric_families("""# TYPE nhneg histogram
+# HELP nhneg Is a native histogram whose first spans start at negative bucket indexes
+nhneg {count:5,sum:-1.5,schema:0,zero_threshold:0.001,zero_count:0,positive_spans:[-2:2],negative_spans:[-1:1,2:1],positive_deltas:[1,1],negative_deltas:[1,0]}
+# EOF
+""")
+        families = list(families)
+
+        hfm = HistogramMetricFamily("nhneg", "Is a native histogram whose first spans start at negative bucket indexes")
+        hfm.add_sample("nhneg", None, None, None, None, NativeHistogram(5, -1.5, 0, 0.001, 0, (BucketSpan(-2, 2),), (BucketSpan(-1, 1), BucketSpan(2, 1)), (1, 1), (1, 0)))
+        self.assertEqual([hfm], families)
+
     def test_native_histogram_with_labels(self):
         families = text_string_to_metric_families("""# TYPE hist_w_labels histogram
 # HELP hist_w_labels Is a basic example of a native histogram with labels