diff --git a/CHANGELOG.md b/CHANGELOG.md
index 28c0dd717af4..44aec3b2bee4 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -12,6 +12,8 @@
    ([#11239](https://github.com/Microsoft/vscode-python/issues/11239))
 1. Warn when using a version of the widget `qgrid` greater than `1.1.1` with the recommendation to downgrade to `1.1.1`.
    ([#11245](https://github.com/Microsoft/vscode-python/issues/11245))
+1. Change "python.dataScience.runStartupCommands" commands to be a global setting, not a workspace setting.
+   ([#11352](https://github.com/Microsoft/vscode-python/issues/11352))
 
 ### Thanks
 
diff --git a/package.json b/package.json
index 0c2d06b0203b..ff36ef99972b 100644
--- a/package.json
+++ b/package.json
@@ -2796,13 +2796,13 @@
                     "default": "",
                     "deprecationMessage": "This setting has been deprecated in favor of 'runStartupCommands'.",
                     "description": "A series of Python instructions or iPython magic commands separated by '\\n' that will be executed when the interactive window loads.",
-                    "scope": "resource"
+                    "scope": "application"
                 },
                 "python.dataScience.runStartupCommands": {
                     "type": "string",
                     "default": "",
                     "description": "A series of Python instructions or iPython magic commands separated by '\\n' that will be executed when the interactive window loads. For instance, set this to '%load_ext autoreload\\n%autoreload 2' to automatically reload changes made to imported files without having to restart the interactive session.",
-                    "scope": "resource"
+                    "scope": "application"
                 },
                 "python.dataScience.debugJustMyCode": {
                     "type": "boolean",