diff --git a/.github/.OwlBot.lock.yaml b/.github/.OwlBot.lock.yaml
index ba7b2f7..cb89b2e 100644
--- a/.github/.OwlBot.lock.yaml
+++ b/.github/.OwlBot.lock.yaml
@@ -1,3 +1,3 @@
 docker:
   image: gcr.io/cloud-devrel-public-resources/owlbot-python:latest
-  digest: sha256:3728d8fd14daa46a96d04ce61c6451a3ac864dc48fb71eecbb4411f4a95618d4
+  digest: sha256:ec49167c606648a063d1222220b48119c912562849a0528f35bfb592a9f72737
diff --git a/.kokoro/docs/common.cfg b/.kokoro/docs/common.cfg
index a397f45..3c57ec8 100644
--- a/.kokoro/docs/common.cfg
+++ b/.kokoro/docs/common.cfg
@@ -30,6 +30,7 @@ env_vars: {
 
 env_vars: {
     key: "V2_STAGING_BUCKET"
+    # Push google cloud library docs to the Cloud RAD bucket `docs-staging-v2`
     value: "docs-staging-v2"
 }
 
diff --git a/CHANGELOG.md b/CHANGELOG.md
index fc2b2eb..a8591d7 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,18 @@
 # Changelog
 
+### [0.4.1](https://www.github.com/googleapis/python-life-sciences/compare/v0.4.0...v0.4.1) (2021-11-01)
+
+
+### Bug Fixes
+
+* **deps:** drop packaging dependency ([3364a46](https://www.github.com/googleapis/python-life-sciences/commit/3364a46234f2667908d6be5dbce125debc9be582))
+* **deps:** require google-api-core >= 1.28.0 ([3364a46](https://www.github.com/googleapis/python-life-sciences/commit/3364a46234f2667908d6be5dbce125debc9be582))
+
+
+### Documentation
+
+* list oneofs in docstring ([3364a46](https://www.github.com/googleapis/python-life-sciences/commit/3364a46234f2667908d6be5dbce125debc9be582))
+
 ## [0.4.0](https://www.github.com/googleapis/python-life-sciences/compare/v0.3.0...v0.4.0) (2021-10-18)
 
 
diff --git a/docs/index.rst b/docs/index.rst
index 2599b81..e54c5b0 100644
--- a/docs/index.rst
+++ b/docs/index.rst
@@ -11,12 +11,13 @@ API Reference
     lifesciences_v2beta/services
     lifesciences_v2beta/types
 
+
 Changelog
 ---------
 
 For a list of all ``google-cloud-life-sciences`` releases:
 
 .. toctree::
-   :maxdepth: 2
+    :maxdepth: 2
 
-   changelog
+    changelog
diff --git a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/async_client.py b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/async_client.py
index d6b0e1c..c0e4189 100644
--- a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/async_client.py
+++ b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/async_client.py
@@ -19,13 +19,15 @@
 from typing import Dict, Sequence, Tuple, Type, Union
 import pkg_resources
 
-import google.api_core.client_options as ClientOptions  # type: ignore
+from google.api_core.client_options import ClientOptions  # type: ignore
 from google.api_core import exceptions as core_exceptions  # type: ignore
 from google.api_core import gapic_v1  # type: ignore
 from google.api_core import retry as retries  # type: ignore
 from google.auth import credentials as ga_credentials  # type: ignore
 from google.oauth2 import service_account  # type: ignore
 
+OptionalRetry = Union[retries.Retry, object]
+
 from google.api_core import operation  # type: ignore
 from google.api_core import operation_async  # type: ignore
 from google.cloud.lifesciences_v2beta.types import workflows
@@ -167,9 +169,9 @@ def __init__(
 
     async def run_pipeline(
         self,
-        request: workflows.RunPipelineRequest = None,
+        request: Union[workflows.RunPipelineRequest, dict] = None,
         *,
-        retry: retries.Retry = gapic_v1.method.DEFAULT,
+        retry: OptionalRetry = gapic_v1.method.DEFAULT,
         timeout: float = None,
         metadata: Sequence[Tuple[str, str]] = (),
     ) -> operation_async.AsyncOperation:
@@ -193,7 +195,7 @@ async def run_pipeline(
         -  ``lifesciences.workflows.run``
 
         Args:
-            request (:class:`google.cloud.lifesciences_v2beta.types.RunPipelineRequest`):
+            request (Union[google.cloud.lifesciences_v2beta.types.RunPipelineRequest, dict]):
                 The request object. The arguments to the `RunPipeline`
                 method. The requesting user must have the
                 `iam.serviceAccounts.actAs` permission for the Cloud
diff --git a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/client.py b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/client.py
index f7271a5..90f8b03 100644
--- a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/client.py
+++ b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/client.py
@@ -30,6 +30,8 @@
 from google.auth.exceptions import MutualTLSChannelError  # type: ignore
 from google.oauth2 import service_account  # type: ignore
 
+OptionalRetry = Union[retries.Retry, object]
+
 from google.api_core import operation  # type: ignore
 from google.api_core import operation_async  # type: ignore
 from google.cloud.lifesciences_v2beta.types import workflows
@@ -340,7 +342,7 @@ def run_pipeline(
         self,
         request: Union[workflows.RunPipelineRequest, dict] = None,
         *,
-        retry: retries.Retry = gapic_v1.method.DEFAULT,
+        retry: OptionalRetry = gapic_v1.method.DEFAULT,
         timeout: float = None,
         metadata: Sequence[Tuple[str, str]] = (),
     ) -> operation.Operation:
diff --git a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/base.py b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/base.py
index eb9fdd1..2278a90 100644
--- a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/base.py
+++ b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/base.py
@@ -15,7 +15,6 @@
 #
 import abc
 from typing import Awaitable, Callable, Dict, Optional, Sequence, Union
-import packaging.version
 import pkg_resources
 
 import google.auth  # type: ignore
@@ -39,15 +38,6 @@
 except pkg_resources.DistributionNotFound:
     DEFAULT_CLIENT_INFO = gapic_v1.client_info.ClientInfo()
 
-try:
-    # google.auth.__version__ was added in 1.26.0
-    _GOOGLE_AUTH_VERSION = google.auth.__version__
-except AttributeError:
-    try:  # try pkg_resources if it is available
-        _GOOGLE_AUTH_VERSION = pkg_resources.get_distribution("google-auth").version
-    except pkg_resources.DistributionNotFound:  # pragma: NO COVER
-        _GOOGLE_AUTH_VERSION = None
-
 
 class WorkflowsServiceV2BetaTransport(abc.ABC):
     """Abstract transport class for WorkflowsServiceV2Beta."""
@@ -97,7 +87,7 @@ def __init__(
             host += ":443"
         self._host = host
 
-        scopes_kwargs = self._get_scopes_kwargs(self._host, scopes)
+        scopes_kwargs = {"scopes": scopes, "default_scopes": self.AUTH_SCOPES}
 
         # Save the scopes.
         self._scopes = scopes
@@ -130,29 +120,6 @@ def __init__(
         # Save the credentials.
         self._credentials = credentials
 
-    # TODO(busunkim): This method is in the base transport
-    # to avoid duplicating code across the transport classes. These functions
-    # should be deleted once the minimum required versions of google-auth is increased.
-
-    # TODO: Remove this function once google-auth >= 1.25.0 is required
-    @classmethod
-    def _get_scopes_kwargs(
-        cls, host: str, scopes: Optional[Sequence[str]]
-    ) -> Dict[str, Optional[Sequence[str]]]:
-        """Returns scopes kwargs to pass to google-auth methods depending on the google-auth version"""
-
-        scopes_kwargs = {}
-
-        if _GOOGLE_AUTH_VERSION and (
-            packaging.version.parse(_GOOGLE_AUTH_VERSION)
-            >= packaging.version.parse("1.25.0")
-        ):
-            scopes_kwargs = {"scopes": scopes, "default_scopes": cls.AUTH_SCOPES}
-        else:
-            scopes_kwargs = {"scopes": scopes or cls.AUTH_SCOPES}
-
-        return scopes_kwargs
-
     def _prep_wrapped_messages(self, client_info):
         # Precompute the wrapped methods.
         self._wrapped_methods = {
@@ -171,7 +138,7 @@ def close(self):
         raise NotImplementedError()
 
     @property
-    def operations_client(self) -> operations_v1.OperationsClient:
+    def operations_client(self):
         """Return the client designed to process long-running operations."""
         raise NotImplementedError()
 
diff --git a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc.py b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc.py
index dac918d..030be13 100644
--- a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc.py
+++ b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc.py
@@ -113,7 +113,7 @@ def __init__(
         self._grpc_channel = None
         self._ssl_channel_credentials = ssl_channel_credentials
         self._stubs: Dict[str, Callable] = {}
-        self._operations_client = None
+        self._operations_client: Optional[operations_v1.OperationsClient] = None
 
         if api_mtls_endpoint:
             warnings.warn("api_mtls_endpoint is deprecated", DeprecationWarning)
diff --git a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc_asyncio.py b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc_asyncio.py
index b6ea700..ec44797 100644
--- a/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc_asyncio.py
+++ b/google/cloud/lifesciences_v2beta/services/workflows_service_v2_beta/transports/grpc_asyncio.py
@@ -21,7 +21,6 @@
 from google.api_core import operations_v1  # type: ignore
 from google.auth import credentials as ga_credentials  # type: ignore
 from google.auth.transport.grpc import SslCredentials  # type: ignore
-import packaging.version
 
 import grpc  # type: ignore
 from grpc.experimental import aio  # type: ignore
@@ -160,7 +159,7 @@ def __init__(
         self._grpc_channel = None
         self._ssl_channel_credentials = ssl_channel_credentials
         self._stubs: Dict[str, Callable] = {}
-        self._operations_client = None
+        self._operations_client: Optional[operations_v1.OperationsAsyncClient] = None
 
         if api_mtls_endpoint:
             warnings.warn("api_mtls_endpoint is deprecated", DeprecationWarning)
diff --git a/google/cloud/lifesciences_v2beta/types/workflows.py b/google/cloud/lifesciences_v2beta/types/workflows.py
index 8022146..8c7b554 100644
--- a/google/cloud/lifesciences_v2beta/types/workflows.py
+++ b/google/cloud/lifesciences_v2beta/types/workflows.py
@@ -629,6 +629,13 @@ class Volume(proto.Message):
     Specify either [``Volume``][google.cloud.lifesciences.v2beta.Volume]
     or [``Disk``][google.cloud.lifesciences.v2beta.Disk], but not both.
 
+    This message has `oneof`_ fields (mutually exclusive fields).
+    For each oneof, at most one member field can be set at the same time.
+    Setting any member of the oneof automatically clears all other
+    members.
+
+    .. _oneof: https://proto-plus-python.readthedocs.io/en/stable/fields.html#oneofs-mutually-exclusive-fields
+
     Attributes:
         volume (str):
             A user-supplied name for the volume. Used when mounting the
@@ -638,10 +645,13 @@ class Volume(proto.Message):
             characters and hyphens and cannot start with a hyphen.
         persistent_disk (google.cloud.lifesciences_v2beta.types.PersistentDisk):
             Configuration for a persistent disk.
+            This field is a member of `oneof`_ ``storage``.
         existing_disk (google.cloud.lifesciences_v2beta.types.ExistingDisk):
             Configuration for a existing disk.
+            This field is a member of `oneof`_ ``storage``.
         nfs_mount (google.cloud.lifesciences_v2beta.types.NFSMount):
             Configuration for an NFS mount.
+            This field is a member of `oneof`_ ``storage``.
     """
 
     volume = proto.Field(proto.STRING, number=1,)
@@ -762,6 +772,13 @@ class Event(proto.Message):
     r"""Carries information about events that occur during pipeline
     execution.
 
+    This message has `oneof`_ fields (mutually exclusive fields).
+    For each oneof, at most one member field can be set at the same time.
+    Setting any member of the oneof automatically clears all other
+    members.
+
+    .. _oneof: https://proto-plus-python.readthedocs.io/en/stable/fields.html#oneofs-mutually-exclusive-fields
+
     Attributes:
         timestamp (google.protobuf.timestamp_pb2.Timestamp):
             The time at which the event occurred.
@@ -773,33 +790,43 @@ class Event(proto.Message):
         delayed (google.cloud.lifesciences_v2beta.types.DelayedEvent):
             See
             [google.cloud.lifesciences.v2beta.DelayedEvent][google.cloud.lifesciences.v2beta.DelayedEvent].
+            This field is a member of `oneof`_ ``details``.
         worker_assigned (google.cloud.lifesciences_v2beta.types.WorkerAssignedEvent):
             See
             [google.cloud.lifesciences.v2beta.WorkerAssignedEvent][google.cloud.lifesciences.v2beta.WorkerAssignedEvent].
+            This field is a member of `oneof`_ ``details``.
         worker_released (google.cloud.lifesciences_v2beta.types.WorkerReleasedEvent):
             See
             [google.cloud.lifesciences.v2beta.WorkerReleasedEvent][google.cloud.lifesciences.v2beta.WorkerReleasedEvent].
+            This field is a member of `oneof`_ ``details``.
         pull_started (google.cloud.lifesciences_v2beta.types.PullStartedEvent):
             See
             [google.cloud.lifesciences.v2beta.PullStartedEvent][google.cloud.lifesciences.v2beta.PullStartedEvent].
+            This field is a member of `oneof`_ ``details``.
         pull_stopped (google.cloud.lifesciences_v2beta.types.PullStoppedEvent):
             See
             [google.cloud.lifesciences.v2beta.PullStoppedEvent][google.cloud.lifesciences.v2beta.PullStoppedEvent].
+            This field is a member of `oneof`_ ``details``.
         container_started (google.cloud.lifesciences_v2beta.types.ContainerStartedEvent):
             See
             [google.cloud.lifesciences.v2beta.ContainerStartedEvent][google.cloud.lifesciences.v2beta.ContainerStartedEvent].
+            This field is a member of `oneof`_ ``details``.
         container_stopped (google.cloud.lifesciences_v2beta.types.ContainerStoppedEvent):
             See
             [google.cloud.lifesciences.v2beta.ContainerStoppedEvent][google.cloud.lifesciences.v2beta.ContainerStoppedEvent].
+            This field is a member of `oneof`_ ``details``.
         container_killed (google.cloud.lifesciences_v2beta.types.ContainerKilledEvent):
             See
             [google.cloud.lifesciences.v2beta.ContainerKilledEvent][google.cloud.lifesciences.v2beta.ContainerKilledEvent].
+            This field is a member of `oneof`_ ``details``.
         unexpected_exit_status (google.cloud.lifesciences_v2beta.types.UnexpectedExitStatusEvent):
             See
             [google.cloud.lifesciences.v2beta.UnexpectedExitStatusEvent][google.cloud.lifesciences.v2beta.UnexpectedExitStatusEvent].
+            This field is a member of `oneof`_ ``details``.
         failed (google.cloud.lifesciences_v2beta.types.FailedEvent):
             See
             [google.cloud.lifesciences.v2beta.FailedEvent][google.cloud.lifesciences.v2beta.FailedEvent].
+            This field is a member of `oneof`_ ``details``.
     """
 
     timestamp = proto.Field(proto.MESSAGE, number=1, message=timestamp_pb2.Timestamp,)
diff --git a/noxfile.py b/noxfile.py
index 2bb4cf7..2a2001c 100644
--- a/noxfile.py
+++ b/noxfile.py
@@ -101,7 +101,7 @@ def default(session):
         "py.test",
         "--quiet",
         f"--junitxml=unit_{session.python}_sponge_log.xml",
-        "--cov=google/cloud",
+        "--cov=google",
         "--cov=tests/unit",
         "--cov-append",
         "--cov-config=.coveragerc",
diff --git a/setup.py b/setup.py
index 5d127ca..cc35a67 100644
--- a/setup.py
+++ b/setup.py
@@ -22,16 +22,15 @@
 
 name = "google-cloud-life-sciences"
 description = "Cloud Life Sciences client library"
-version = "0.4.0"
+version = "0.4.1"
 release_status = "Development Status :: 4 - Beta"
 url = "https://github.com/googleapis/python-life-sciences"
 dependencies = [
     # NOTE: Maintainers, please do not require google-api-core>=2.x.x
     # Until this issue is closed
     # https://github.com/googleapis/google-cloud-python/issues/10566
-    "google-api-core[grpc] >= 1.26.0, <3.0.0dev",
+    "google-api-core[grpc] >= 1.28.0, <3.0.0dev",
     "proto-plus >= 1.15.0",
-    "packaging >= 14.3",
 ]
 
 package_root = os.path.abspath(os.path.dirname(__file__))
diff --git a/testing/constraints-3.6.txt b/testing/constraints-3.6.txt
index fe11de2..1e3ec8b 100644
--- a/testing/constraints-3.6.txt
+++ b/testing/constraints-3.6.txt
@@ -4,7 +4,5 @@
 # Pin the version to the lower bound.
 # e.g., if setup.py has "google-cloud-foo >= 1.14.0, < 2.0.0dev",
 # Then this file should have google-cloud-foo==1.14.0
-google-api-core==1.26.0
+google-api-core==1.28.0
 proto-plus==1.15.0
-packaging==14.3
-google-auth==1.24.0  # TODO: remove when google-auth>=1.25.0 si transitively required through google-api-core
\ No newline at end of file
diff --git a/tests/unit/gapic/lifesciences_v2beta/test_workflows_service_v2_beta.py b/tests/unit/gapic/lifesciences_v2beta/test_workflows_service_v2_beta.py
index 44d3376..2f52ad6 100644
--- a/tests/unit/gapic/lifesciences_v2beta/test_workflows_service_v2_beta.py
+++ b/tests/unit/gapic/lifesciences_v2beta/test_workflows_service_v2_beta.py
@@ -15,7 +15,6 @@
 #
 import os
 import mock
-import packaging.version
 
 import grpc
 from grpc.experimental import aio
@@ -44,9 +43,6 @@
 from google.cloud.lifesciences_v2beta.services.workflows_service_v2_beta import (
     transports,
 )
-from google.cloud.lifesciences_v2beta.services.workflows_service_v2_beta.transports.base import (
-    _GOOGLE_AUTH_VERSION,
-)
 from google.cloud.lifesciences_v2beta.types import workflows
 from google.longrunning import operations_pb2
 from google.oauth2 import service_account
@@ -54,20 +50,6 @@
 import google.auth
 
 
-# TODO(busunkim): Once google-auth >= 1.25.0 is required transitively
-# through google-api-core:
-# - Delete the auth "less than" test cases
-# - Delete these pytest markers (Make the "greater than or equal to" tests the default).
-requires_google_auth_lt_1_25_0 = pytest.mark.skipif(
-    packaging.version.parse(_GOOGLE_AUTH_VERSION) >= packaging.version.parse("1.25.0"),
-    reason="This test requires google-auth < 1.25.0",
-)
-requires_google_auth_gte_1_25_0 = pytest.mark.skipif(
-    packaging.version.parse(_GOOGLE_AUTH_VERSION) < packaging.version.parse("1.25.0"),
-    reason="This test requires google-auth >= 1.25.0",
-)
-
-
 def client_cert_source_callback():
     return b"cert bytes", b"key bytes"
 
@@ -229,7 +211,7 @@ def test_workflows_service_v2_beta_client_client_options(
     options = client_options.ClientOptions(api_endpoint="squid.clam.whelk")
     with mock.patch.object(transport_class, "__init__") as patched:
         patched.return_value = None
-        client = client_class(client_options=options)
+        client = client_class(transport=transport_name, client_options=options)
         patched.assert_called_once_with(
             credentials=None,
             credentials_file=None,
@@ -246,7 +228,7 @@ def test_workflows_service_v2_beta_client_client_options(
     with mock.patch.dict(os.environ, {"GOOGLE_API_USE_MTLS_ENDPOINT": "never"}):
         with mock.patch.object(transport_class, "__init__") as patched:
             patched.return_value = None
-            client = client_class()
+            client = client_class(transport=transport_name)
             patched.assert_called_once_with(
                 credentials=None,
                 credentials_file=None,
@@ -263,7 +245,7 @@ def test_workflows_service_v2_beta_client_client_options(
     with mock.patch.dict(os.environ, {"GOOGLE_API_USE_MTLS_ENDPOINT": "always"}):
         with mock.patch.object(transport_class, "__init__") as patched:
             patched.return_value = None
-            client = client_class()
+            client = client_class(transport=transport_name)
             patched.assert_called_once_with(
                 credentials=None,
                 credentials_file=None,
@@ -292,7 +274,7 @@ def test_workflows_service_v2_beta_client_client_options(
     options = client_options.ClientOptions(quota_project_id="octopus")
     with mock.patch.object(transport_class, "__init__") as patched:
         patched.return_value = None
-        client = client_class(client_options=options)
+        client = client_class(transport=transport_name, client_options=options)
         patched.assert_called_once_with(
             credentials=None,
             credentials_file=None,
@@ -361,7 +343,7 @@ def test_workflows_service_v2_beta_client_mtls_env_auto(
         )
         with mock.patch.object(transport_class, "__init__") as patched:
             patched.return_value = None
-            client = client_class(client_options=options)
+            client = client_class(transport=transport_name, client_options=options)
 
             if use_client_cert_env == "false":
                 expected_client_cert_source = None
@@ -403,7 +385,7 @@ def test_workflows_service_v2_beta_client_mtls_env_auto(
                         expected_client_cert_source = client_cert_source_callback
 
                     patched.return_value = None
-                    client = client_class()
+                    client = client_class(transport=transport_name)
                     patched.assert_called_once_with(
                         credentials=None,
                         credentials_file=None,
@@ -425,7 +407,7 @@ def test_workflows_service_v2_beta_client_mtls_env_auto(
                 return_value=False,
             ):
                 patched.return_value = None
-                client = client_class()
+                client = client_class(transport=transport_name)
                 patched.assert_called_once_with(
                     credentials=None,
                     credentials_file=None,
@@ -460,7 +442,7 @@ def test_workflows_service_v2_beta_client_client_options_scopes(
     options = client_options.ClientOptions(scopes=["1", "2"],)
     with mock.patch.object(transport_class, "__init__") as patched:
         patched.return_value = None
-        client = client_class(client_options=options)
+        client = client_class(transport=transport_name, client_options=options)
         patched.assert_called_once_with(
             credentials=None,
             credentials_file=None,
@@ -495,7 +477,7 @@ def test_workflows_service_v2_beta_client_client_options_credentials_file(
     options = client_options.ClientOptions(credentials_file="credentials.json")
     with mock.patch.object(transport_class, "__init__") as patched:
         patched.return_value = None
-        client = client_class(client_options=options)
+        client = client_class(transport=transport_name, client_options=options)
         patched.assert_called_once_with(
             credentials=None,
             credentials_file="credentials.json",
@@ -774,7 +756,6 @@ def test_workflows_service_v2_beta_base_transport():
         transport.operations_client
 
 
-@requires_google_auth_gte_1_25_0
 def test_workflows_service_v2_beta_base_transport_with_credentials_file():
     # Instantiate the base transport with a credentials file
     with mock.patch.object(
@@ -795,26 +776,6 @@ def test_workflows_service_v2_beta_base_transport_with_credentials_file():
         )
 
 
-@requires_google_auth_lt_1_25_0
-def test_workflows_service_v2_beta_base_transport_with_credentials_file_old_google_auth():
-    # Instantiate the base transport with a credentials file
-    with mock.patch.object(
-        google.auth, "load_credentials_from_file", autospec=True
-    ) as load_creds, mock.patch(
-        "google.cloud.lifesciences_v2beta.services.workflows_service_v2_beta.transports.WorkflowsServiceV2BetaTransport._prep_wrapped_messages"
-    ) as Transport:
-        Transport.return_value = None
-        load_creds.return_value = (ga_credentials.AnonymousCredentials(), None)
-        transport = transports.WorkflowsServiceV2BetaTransport(
-            credentials_file="credentials.json", quota_project_id="octopus",
-        )
-        load_creds.assert_called_once_with(
-            "credentials.json",
-            scopes=("https://www.googleapis.com/auth/cloud-platform",),
-            quota_project_id="octopus",
-        )
-
-
 def test_workflows_service_v2_beta_base_transport_with_adc():
     # Test the default credentials are used if credentials and credentials_file are None.
     with mock.patch.object(google.auth, "default", autospec=True) as adc, mock.patch(
@@ -826,7 +787,6 @@ def test_workflows_service_v2_beta_base_transport_with_adc():
         adc.assert_called_once()
 
 
-@requires_google_auth_gte_1_25_0
 def test_workflows_service_v2_beta_auth_adc():
     # If no credentials are provided, we should use ADC credentials.
     with mock.patch.object(google.auth, "default", autospec=True) as adc:
@@ -839,18 +799,6 @@ def test_workflows_service_v2_beta_auth_adc():
         )
 
 
-@requires_google_auth_lt_1_25_0
-def test_workflows_service_v2_beta_auth_adc_old_google_auth():
-    # If no credentials are provided, we should use ADC credentials.
-    with mock.patch.object(google.auth, "default", autospec=True) as adc:
-        adc.return_value = (ga_credentials.AnonymousCredentials(), None)
-        WorkflowsServiceV2BetaClient()
-        adc.assert_called_once_with(
-            scopes=("https://www.googleapis.com/auth/cloud-platform",),
-            quota_project_id=None,
-        )
-
-
 @pytest.mark.parametrize(
     "transport_class",
     [
@@ -858,7 +806,6 @@ def test_workflows_service_v2_beta_auth_adc_old_google_auth():
         transports.WorkflowsServiceV2BetaGrpcAsyncIOTransport,
     ],
 )
-@requires_google_auth_gte_1_25_0
 def test_workflows_service_v2_beta_transport_auth_adc(transport_class):
     # If credentials and host are not provided, the transport class should use
     # ADC credentials.
@@ -872,26 +819,6 @@ def test_workflows_service_v2_beta_transport_auth_adc(transport_class):
         )
 
 
-@pytest.mark.parametrize(
-    "transport_class",
-    [
-        transports.WorkflowsServiceV2BetaGrpcTransport,
-        transports.WorkflowsServiceV2BetaGrpcAsyncIOTransport,
-    ],
-)
-@requires_google_auth_lt_1_25_0
-def test_workflows_service_v2_beta_transport_auth_adc_old_google_auth(transport_class):
-    # If credentials and host are not provided, the transport class should use
-    # ADC credentials.
-    with mock.patch.object(google.auth, "default", autospec=True) as adc:
-        adc.return_value = (ga_credentials.AnonymousCredentials(), None)
-        transport_class(quota_project_id="octopus")
-        adc.assert_called_once_with(
-            scopes=("https://www.googleapis.com/auth/cloud-platform",),
-            quota_project_id="octopus",
-        )
-
-
 @pytest.mark.parametrize(
     "transport_class,grpc_helpers",
     [