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structure/seqres.md

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SEQRES and ATOM records, mapping to Uniprot (SIFTs)
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SEQRES and ATOM Records, Mapping to Uniprot (SIFTs)
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How molecular sequences are linked to experimentally observed atoms.
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The blue-boxes are regions for which atoms records are available. For the grey regions there is sequence information available in the PDB, but no coordinates.
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## Seqres and Atom records
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## Seqres and Atom Records
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The sequence that has been used in the experiment is stored in the **Seqres** records in the PDB. It is often not the same sequences as can be found in Uniprot, since it can contain cloning-artefacts and modifications that were necessary in order to crystallize a structure.
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```
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## Accessing Seqres and Atom groups
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## Accessing Seqres and Atom Groups
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By default BioJava loads both the Seqres and Atom groups into the [Chain](http://www.biojava.org/docs/api/org/biojava/nbio/structure/Chain.html)
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objects.
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Groups that are part of the Seqres sequence as well as of the Atom records are mapped onto each other. This means you
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can iterate over all Seqres groups in a chain and check, if they have observed atoms.
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## Mapping from Uniprot to Atom records
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## Mapping from Uniprot to Atom Records
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The mapping between PDB and UniProt changes over time, due to the dynamic nature of biological data. The [PDBe](http://www.pdbe.org) has a project that provides up-to-date mappings between the two databases, the [SIFTs](http://www.ebi.ac.uk/pdbe/docs/sifts/) project.
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Navigation:
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[Home](../README.md)
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| [Book 3: The Protein Structure modules](README.md)
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| [Book 3: The Structure modules](README.md)
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| Chapter 7 : SEQRES and ATOM records
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Prev: [Chapter 6 : work with mmCIF/PDBx files](mmcif.md)

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