/*
 *                    BioJava development code
 *
 * This code may be freely distributed and modified under the
 * terms of the GNU Lesser General Public Licence.  This should
 * be distributed with the code.  If you do not have a copy,
 * see:
 *
 *      http://www.gnu.org/copyleft/lesser.html
 *
 * Copyright for this code is held jointly by the individual
 * authors.  These should be listed in @author doc comments.
 *
 * For more information on the BioJava project and its aims,
 * or to join the biojava-l mailing list, visit the home page
 * at:
 *
 *      http://www.biojava.org/
 *
 * Created on June 7, 2010
 * Author: Mark Chapman
 */

package org.biojava.nbio.core.alignment.template;

import org.biojava.nbio.core.sequence.location.template.Location;
import org.biojava.nbio.core.sequence.location.template.Point;
import org.biojava.nbio.core.sequence.template.Compound;
import org.biojava.nbio.core.sequence.template.Sequence;

/**
 * Defines a data structure for a {@link Sequence} within an alignment.
 *
 * @author Mark Chapman
 * @author Paolo Pavan
 * @param <C> each element of the {@link Sequence} is a {@link Compound} of type C
 * @param <S> the sequence type
 */
public interface AlignedSequence<S extends Sequence<C>, C extends Compound> extends Sequence<C> {

	/**
	 * Defines an alignment step in order to pass alignment information from an Aligner to a constructor.
	 */
	enum Step { COMPOUND, GAP }

	/**
	 * Nullifies cached arrays/objects.
	 */
	void clearCache();

	/** Returns the alignment.
	 *
	 * @return the alignment
	 */
	int[] getAlignmentFromSequence();

	/** Returns the sequence positions at each alignment index
	 *
	 * @return array of the sequence positions
	 */
	int[] getSequenceFromAlignment();

	/**
	 * Returns the column index within an alignment corresponding to the given index in the original {@link Sequence}.
	 * Both indices are 1-indexed and inclusive.
	 *
	 * @param sequenceIndex index in the original {@link Sequence}
	 * @return column index within an alignment
	 * @throws IndexOutOfBoundsException if sequenceIndex &lt; 1 or sequenceIndex >
	 *         {@link #getOriginalSequence()}.{@link #getLength()}
	 */
	int getAlignmentIndexAt(int sequenceIndex);

	/**
	 * Returns the {@link Point} within an alignment of the last element of the original {@link Sequence}.
	 *
	 * @return position within an alignment of final original {@link Sequence} element
	 */
	Point getEnd();

	/**
	 * Returns the {@link Location} of the original {@link Sequence} within an alignment.  This provides access to
	 * additional substructure beyond start and end points.
	 *
	 * @return location within an alignment
	 */
	Location getLocationInAlignment();

	/**
	 * Returns number of gaps (gap openings) in the sequence. This could be determined from the {@link Location} information or from
	 * gap {@link Compound}s, which may not necessarily result in the same number.
	 *
	 * @return number of gaps in the sequence
	 */
	int getNumGaps();

	/**
	 * Returns number of gap positions (gap openings and extensions) in the sequence. This could be determined from the {@link Location}
	 * information or from gap {@link Compound}s, which may not necessarily result in the same number.
	 *
	 * @return number of gap positions in the sequence
	 */
	int getNumGapPositions();

	/**
	 * Returns the coverage, as a fraction between 0 and 1, of this {@link AlignedSequence} with respect to the original sequence.
	 * This is equivalent to ({@link #getLength()} - {@link #getNumGapPositions()}) / getOriginalSequence().getLength().
	 *
	 * @return coverage of the original sequence by the aligned sequence
	 */
	double getCoverage();

	/**
	 * Returns the original {@link Sequence} before alignment.
	 *
	 * @return the original sequence
	 */
	S getOriginalSequence();

	/**
	 * Returns the maximum number of elements contributed to a column of an alignment by this {@link Sequence}.  If
	 * this {@link Sequence} is circular, this number is >= 1.  If not, this overlap count is definitely 1.
	 *
	 * @return the most elements contributed to any alignment column
	 */
	int getOverlapCount();

	/**
	 * Returns the index in the original {@link Sequence} corresponding to the given index within an alignment.  Both
	 * indices are 1-indexed and inclusive.
	 *
	 * @param alignmentIndex column index within an alignment
	 * @return index in the original {@link Sequence}
	 * @throws IndexOutOfBoundsException if alignmentIndex &lt; 1 or alignmentIndex &gt; {@link #getLength()}
	 */
	int getSequenceIndexAt(int alignmentIndex);

	/**
	 * Returns the {@link Point} within an alignment of the first element of the original {@link Sequence}.
	 *
	 * @return position within an alignment of first original {@link Sequence} element
	 */
	Point getStart();

	/**
	 * Returns true if this {@link Sequence} wraps around from the last alignment column back to the first.  This makes
	 * overlap possible, but does not require an overlap count > 1.
	 *
	 * @return true for circular alignment elements
	 */
	boolean isCircular();

	/**
	 * Returns true if this {@link Sequence} has a gap at a particular alignment column.
	 *
	 * @param alignmentIndex column index within an alignment
	 * @return true if this column has a gap
	 * @throws IndexOutOfBoundsException if alignmentIndex &lt; 1 or alignmentIndex &gt; {@link #getLength()}
	 */
	boolean isGap(int alignmentIndex);

}
