diff --git a/devtools/projects/ng-devtools/src/lib/application-operations/index.ts b/devtools/projects/ng-devtools/src/lib/application-operations/index.ts
index ae00f791819f..dca0c90951f6 100644
--- a/devtools/projects/ng-devtools/src/lib/application-operations/index.ts
+++ b/devtools/projects/ng-devtools/src/lib/application-operations/index.ts
@@ -14,6 +14,8 @@ export abstract class ApplicationOperations {
   abstract selectDomElement(position: ElementPosition, target: Frame): void;
   abstract inspect(directivePosition: DirectivePosition, objectPath: string[], target: Frame): void;
   abstract inspectSignal(position: SignalNodePosition, target: Frame): void;
+  abstract setSignalBreakpoint(position: SignalNodePosition, target: Frame): void;
+  abstract removeSignalBreakpoint(position: SignalNodePosition, target: Frame): void;
   abstract viewSourceFromRouter(name: string, type: string, target: Frame): void;
   abstract setStorageItems(items: {[key: string]: unknown}): Promise<void>;
   abstract getStorageItems(items: string[]): Promise<{[key: string]: unknown}>;
diff --git a/devtools/projects/ng-devtools/src/lib/application-services/test-utils/app_operations_mock.ts b/devtools/projects/ng-devtools/src/lib/application-services/test-utils/app_operations_mock.ts
index 7e3aff5a4550..eca8c2f8fa42 100644
--- a/devtools/projects/ng-devtools/src/lib/application-services/test-utils/app_operations_mock.ts
+++ b/devtools/projects/ng-devtools/src/lib/application-services/test-utils/app_operations_mock.ts
@@ -58,6 +58,14 @@ export class AppOperationsMock extends ApplicationOperations {
     throw new Error('Method not implemented.');
   }
 
+  override setSignalBreakpoint(position: SignalNodePosition, target: Frame): void {
+    throw new Error('Method not implemented.');
+  }
+
+  override removeSignalBreakpoint(position: SignalNodePosition, target: Frame): void {
+    throw new Error('Method not implemented.');
+  }
+
   override viewSourceFromRouter(name: string, type: string, target: Frame): void {
     throw new Error('Method not implemented.');
   }
diff --git a/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.html b/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.html
index 8a58b84b2b1c..931e6ad4c7f1 100644
--- a/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.html
+++ b/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.html
@@ -14,7 +14,10 @@
     [node]="node"
     [graph]="signalGraph.graph()!"
     [element]="signalGraph.element()!"
+    [hasBreakpoint]="hasBreakpoint(node)"
     (gotoSource)="gotoSource($event)"
+    (setBreakpoint)="setBreakpoint($event)"
+    (removeBreakpoint)="removeBreakpoint($event)"
     (expandCluster)="expandCluster($event)"
     (highlightDeps)="highlightDeps($event)"
     (close)="detailsVisible.set(false)"
diff --git a/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.ts b/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.ts
index 87673a31e5cf..eb2ed8920ef9 100644
--- a/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.ts
+++ b/devtools/projects/ng-devtools/src/lib/devtools-tabs/directive-explorer/signal-graph-pane/signal-graph-pane.component.ts
@@ -86,6 +86,18 @@ export class SignalGraphPaneComponent {
 
   protected readonly detailsVisible = signal(false);
 
+  // Track active breakpoints for the current inspected element.
+  // Resets when the inspected element changes.
+  protected readonly activeBreakpoints = linkedSignal<ElementPosition | undefined, Set<string>>({
+    source: () => this.signalGraph.element(),
+    computation: () => new Set(),
+  });
+
+  protected hasBreakpoint(node: DevtoolsSignalGraphNode | undefined): boolean {
+    if (!node) return false;
+    return this.activeBreakpoints().has(node.id);
+  }
+
   protected empty = computed(() => !(this.signalGraph.graph()?.nodes.length! > 0));
 
   onNodeClick(node: DevtoolsSignalGraphNode) {
@@ -104,6 +116,38 @@ export class SignalGraphPaneComponent {
     );
   }
 
+  setBreakpoint(node: DevtoolsSignalGraphNode) {
+    const frame = this.frameManager.selectedFrame();
+    this.appOperations.setSignalBreakpoint(
+      {
+        element: this.signalGraph.element()!,
+        signalId: node.id,
+      },
+      frame!,
+    );
+    this.activeBreakpoints.update((set) => {
+      const newSet = new Set(set);
+      newSet.add(node.id);
+      return newSet;
+    });
+  }
+
+  removeBreakpoint(node: DevtoolsSignalGraphNode) {
+    const frame = this.frameManager.selectedFrame();
+    this.appOperations.removeSignalBreakpoint(
+      {
+        element: this.signalGraph.element()!,
+        signalId: node.id,
+      },
+      frame!,
+    );
+    this.activeBreakpoints.update((set) => {
+      const newSet = new Set(set);
+      newSet.delete(node.id);
+      return newSet;
+    });
+  }
+
   expandCluster(clusterId: string) {
     this.visualizer().expandCluster(clusterId);
   }
diff --git a/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.html b/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.html
index fb6e55b44e7e..f1e32ae76374 100644
--- a/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.html
+++ b/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.html
@@ -16,6 +16,17 @@
       >
         <mat-icon> code </mat-icon>
       </button>
+      <button
+        ng-button
+        size="compact"
+        class="action-btn"
+        btnType="secondary"
+        (click)="hasBreakpoint() ? removeBreakpoint.emit(node) : setBreakpoint.emit(node)"
+        [disabled]="!node.debuggable"
+        [matTooltip]="hasBreakpoint() ? 'Remove breakpoint' : 'Set breakpoint'"
+      >
+        <mat-icon [style.color]="hasBreakpoint() ? '#f44336' : 'inherit'"> fiber_manual_record </mat-icon>
+      </button>
     } @else if (isClusterNode) {
       <button
         ng-button
diff --git a/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.ts b/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.ts
index 6658316c876a..ebcc14aa248b 100644
--- a/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.ts
+++ b/devtools/projects/ng-devtools/src/lib/shared/signal-details/signal-details.component.ts
@@ -57,6 +57,9 @@ export class SignalDetailsComponent {
   protected readonly element = input.required<ElementPosition>();
 
   protected readonly gotoSource = output<DevtoolsSignalGraphNode>();
+  protected readonly setBreakpoint = output<DevtoolsSignalGraphNode>();
+  protected readonly removeBreakpoint = output<DevtoolsSignalGraphNode>();
+  protected readonly hasBreakpoint = input<boolean>(false);
   protected readonly expandCluster = output<string>();
   protected readonly highlightDeps = output<{
     node: DevtoolsSignalGraphNode;
diff --git a/devtools/projects/shell-browser/src/app/background.ts b/devtools/projects/shell-browser/src/app/background.ts
index 84a566761b8e..ebafb1b30fba 100644
--- a/devtools/projects/shell-browser/src/app/background.ts
+++ b/devtools/projects/shell-browser/src/app/background.ts
@@ -81,4 +81,162 @@ if (chrome !== undefined && chrome.runtime !== undefined) {
 
   const tabs = {};
   TabManager.initialize(tabs);
+
+  const scriptMap = new Map<string, string>();
+
+  chrome.debugger.onEvent.addListener((source, method, params) => {
+    if (method === 'Debugger.scriptParsed' && params) {
+      const {scriptId, url} = params as any;
+      scriptMap.set(scriptId, url);
+    }
+  });
+
+  const activeBreakpoints = new Map<number, Map<string, string>>();
+
+  function serializePosition(position: any): string {
+    return JSON.stringify({
+      element: position.element,
+      signalId: position.signalId,
+    });
+  }
+
+  chrome.runtime.onMessage.addListener((message, sender, sendResponse) => {
+    if (message.action === 'setSignalBreakpoint') {
+      const {tabId, position} = message;
+      setBreakpointViaCDP(tabId, position)
+        .then((result) => sendResponse({success: true, result}))
+        .catch((err) => {
+          console.error('CDP Error:', err);
+          sendResponse({success: false, error: err.message || err});
+        });
+      return true; // Keep channel open
+    } else if (message.action === 'removeSignalBreakpoint') {
+      const {tabId, position} = message;
+      removeBreakpointViaCDP(tabId, position)
+        .then((result) => sendResponse({success: true, result}))
+        .catch((err) => {
+          console.error('CDP Error:', err);
+          sendResponse({success: false, error: err.message || err});
+        });
+      return true; // Keep channel open
+    }
+    return false;
+  });
+
+  function attachDebugger(target: chrome.debugger.Debuggee, version: string): Promise<void> {
+    return new Promise((resolve, reject) => {
+      chrome.debugger.attach(target, version, () => {
+        if (chrome.runtime.lastError) {
+          reject(chrome.runtime.lastError);
+        } else {
+          resolve();
+        }
+      });
+    });
+  }
+
+  function sendDebuggerCommand(
+    target: chrome.debugger.Debuggee,
+    method: string,
+    commandParams?: {[key: string]: any},
+  ): Promise<any> {
+    return new Promise((resolve, reject) => {
+      chrome.debugger.sendCommand(target, method, commandParams, (result) => {
+        if (chrome.runtime.lastError) {
+          reject(chrome.runtime.lastError);
+        } else {
+          resolve(result);
+        }
+      });
+    });
+  }
+
+  async function setBreakpointViaCDP(tabId: number, position: any) {
+    const target = {tabId};
+
+    try {
+      await attachDebugger(target, '1.3');
+    } catch (err: any) {
+      if (!err.message || !err.message.includes('Already attached')) {
+        throw err;
+      }
+    }
+
+    await sendDebuggerCommand(target, 'Debugger.enable');
+
+    const expression = `inspectedApplication.findSignalNodeByPosition('${JSON.stringify(position)}')`;
+    const evalResult = await sendDebuggerCommand(target, 'Runtime.evaluate', {
+      expression,
+      objectGroup: 'angular-devtools',
+    });
+
+    if (evalResult.exceptionDetails) {
+      throw new Error('Evaluation failed: ' + evalResult.exceptionDetails.exception.description);
+    }
+
+    const objectId = evalResult.result.objectId;
+    if (!objectId) {
+      throw new Error('Could not find function object');
+    }
+
+    const propsResult = await sendDebuggerCommand(target, 'Runtime.getProperties', {
+      objectId,
+    });
+
+    const internalProps = propsResult.internalProperties || [];
+    const locationProp = internalProps.find((p: any) => p.name === '[[FunctionLocation]]');
+
+    if (!locationProp || !locationProp.value || !locationProp.value.value) {
+      throw new Error('Could not find [[FunctionLocation]]');
+    }
+
+    const {scriptId, lineNumber, columnNumber} = locationProp.value.value;
+
+    let bpResult;
+    const url = scriptMap.get(scriptId);
+    if (!url) {
+      console.warn('Could not find URL for scriptId:', scriptId, 'falling back to scriptId');
+      bpResult = await sendDebuggerCommand(target, 'Debugger.setBreakpoint', {
+        location: {scriptId, lineNumber, columnNumber},
+      });
+    } else {
+      bpResult = await sendDebuggerCommand(target, 'Debugger.setBreakpointByUrl', {
+        url,
+        lineNumber,
+        columnNumber,
+      });
+    }
+
+    if (bpResult && bpResult.breakpointId) {
+      if (!activeBreakpoints.has(tabId)) {
+        activeBreakpoints.set(tabId, new Map());
+      }
+      const posKey = serializePosition(position);
+      activeBreakpoints.get(tabId)!.set(posKey, bpResult.breakpointId);
+    }
+
+    return bpResult;
+  }
+
+  async function removeBreakpointViaCDP(tabId: number, position: any) {
+    const target = {tabId};
+    const tabBps = activeBreakpoints.get(tabId);
+    if (!tabBps) {
+      throw new Error('No active breakpoints for this tab');
+    }
+    const posKey = serializePosition(position);
+    const breakpointId = tabBps.get(posKey);
+    if (!breakpointId) {
+      throw new Error('No active breakpoint found for this signal');
+    }
+
+    await sendDebuggerCommand(target, 'Debugger.removeBreakpoint', {
+      breakpointId,
+    });
+
+    tabBps.delete(posKey);
+    if (tabBps.size === 0) {
+      activeBreakpoints.delete(tabId);
+    }
+  }
 }
diff --git a/devtools/projects/shell-browser/src/app/chrome-application-operations.ts b/devtools/projects/shell-browser/src/app/chrome-application-operations.ts
index a6a5f113b0e5..4105d49ead5c 100644
--- a/devtools/projects/shell-browser/src/app/chrome-application-operations.ts
+++ b/devtools/projects/shell-browser/src/app/chrome-application-operations.ts
@@ -49,6 +49,42 @@ export class ChromeApplicationOperations extends ApplicationOperations {
     this.runInInspectedWindow(inspectSignal, target);
   }
 
+  override setSignalBreakpoint(position: SignalNodePosition, target: Frame): void {
+    const tabId = chrome.devtools.inspectedWindow.tabId;
+    chrome.runtime.sendMessage(
+      {
+        action: 'setSignalBreakpoint',
+        tabId,
+        position,
+      },
+      (response) => {
+        if (response && response.success) {
+          console.log('Breakpoint set successfully via CDP');
+        } else {
+          console.error('Failed to set breakpoint via CDP:', response?.error);
+        }
+      },
+    );
+  }
+
+  override removeSignalBreakpoint(position: SignalNodePosition, target: Frame): void {
+    const tabId = chrome.devtools.inspectedWindow.tabId;
+    chrome.runtime.sendMessage(
+      {
+        action: 'removeSignalBreakpoint',
+        tabId,
+        position,
+      },
+      (response) => {
+        if (response && response.success) {
+          console.log('Breakpoint removed successfully via CDP');
+        } else {
+          console.error('Failed to remove breakpoint via CDP:', response?.error);
+        }
+      },
+    );
+  }
+
   override viewSourceFromRouter(name: string, type: string, target: Frame): void {
     const viewSource = `inspect(inspectedApplication.findConstructorByNameForRouter('${name}', '${type}'))`;
     this.runInInspectedWindow(viewSource, target);
diff --git a/devtools/projects/shell-browser/src/manifest/manifest.chrome.json b/devtools/projects/shell-browser/src/manifest/manifest.chrome.json
index f413f822ca78..5e1f811af23b 100644
--- a/devtools/projects/shell-browser/src/manifest/manifest.chrome.json
+++ b/devtools/projects/shell-browser/src/manifest/manifest.chrome.json
@@ -33,7 +33,7 @@
   "background": {
     "service_worker": "app/background_bundle.js"
   },
-  "permissions": ["scripting", "activeTab", "storage"],
+  "permissions": ["scripting", "activeTab", "storage", "debugger"],
   "host_permissions": ["<all_urls>"],
   "content_scripts": [
     {
diff --git a/devtools/projects/shell-browser/src/manifest/manifest.firefox.json b/devtools/projects/shell-browser/src/manifest/manifest.firefox.json
index ce9396d5690a..9a0a39c2cca6 100644
--- a/devtools/projects/shell-browser/src/manifest/manifest.firefox.json
+++ b/devtools/projects/shell-browser/src/manifest/manifest.firefox.json
@@ -18,7 +18,7 @@
   "background": {
     "scripts": ["app/background_bundle.js"]
   },
-  "permissions": ["activeTab", "storage", "http://*/*", "https://*/*", "file:///*"],
+  "permissions": ["activeTab", "storage", "http://*/*", "https://*/*", "file:///*", "debugger"],
   "content_scripts": [
     {
       "matches": ["<all_urls>"],
diff --git a/devtools/src/demo-application-operations.ts b/devtools/src/demo-application-operations.ts
index 9b70739b29e3..92b6f9c4a4b2 100644
--- a/devtools/src/demo-application-operations.ts
+++ b/devtools/src/demo-application-operations.ts
@@ -36,6 +36,20 @@ export class DemoApplicationOperations extends ApplicationOperations {
     return;
   }
 
+  override setSignalBreakpoint(position: SignalNodePosition): void {
+    console.warn(
+      'setSignalBreakpoint() is not implemented because the demo app runs in an Iframe',
+    );
+    return;
+  }
+
+  override removeSignalBreakpoint(position: SignalNodePosition): void {
+    console.warn(
+      'removeSignalBreakpoint() is not implemented because the demo app runs in an Iframe',
+    );
+    return;
+  }
+
   override viewSourceFromRouter(name: string, type: string): void {
     console.warn(
       'viewSourceFromRouter() is not implemented because the demo app runs in an Iframe',
diff --git a/packages/core/src/render3/util/signal_debug.ts b/packages/core/src/render3/util/signal_debug.ts
index d5519d4c4a7d..4aca04f57240 100644
--- a/packages/core/src/render3/util/signal_debug.ts
+++ b/packages/core/src/render3/util/signal_debug.ts
@@ -134,6 +134,14 @@ function getNodesAndEdgesFromSignalMap(signalMap: ReadonlyMap<ReactiveNode, Reac
         debuggableFn: consumer.lView?.[CONTEXT]?.constructor as (() => unknown) | undefined,
         id,
       });
+    } else if (isEffectNode(consumer)) {
+      debugSignalGraphNodes.push({
+        label: consumer.debugName,
+        kind: consumer.kind,
+        epoch: consumer.version,
+        debuggableFn: consumer.fn,
+        id,
+      });
     } else {
       debugSignalGraphNodes.push({
         label: consumer.debugName,
diff --git a/packages/core/test/acceptance/signal_debug_spec.ts b/packages/core/test/acceptance/signal_debug_spec.ts
index a92634ccb6e9..ba3f6c2d815d 100644
--- a/packages/core/test/acceptance/signal_debug_spec.ts
+++ b/packages/core/test/acceptance/signal_debug_spec.ts
@@ -122,6 +122,8 @@ describe('getSignalGraph', () => {
 
     const effectNode = nodes.find((node) => node.label === 'primitiveSignalEffect')!;
     expect(effectNode).toBeDefined();
+    expect(effectNode.debuggableFn).toBeDefined();
+    expect(typeof effectNode.debuggableFn).toBe('function');
 
     const signalNode = nodes.find((node) => node.label === 'primitiveSignal')!;
     expect(signalNode).toBeDefined();