diff --git a/.github/workflows/build-python-packages.yml b/.github/workflows/build-python-packages.yml
index 862a0828..05c85b8e 100644
--- a/.github/workflows/build-python-packages.yml
+++ b/.github/workflows/build-python-packages.yml
@@ -20,7 +20,7 @@ on:
       PLATFORMS:
         description: 'Platforms for execution in "os" or "os_arch" format (arch is "x64" by default)'
         required: true
-        default: 'ubuntu-22.04,ubuntu-22.04_arm64,ubuntu-24.04,ubuntu-24.04_arm64,macos-15-intel_x64,macos-14_arm64,windows-2022_x64,windows-2022_x86,windows-11_arm64'
+        default: 'ubuntu-22.04,ubuntu-22.04_arm64,ubuntu-24.04,ubuntu-24.04_arm64,rhel-9,rhel-10,macos-15-intel_x64,macos-14_arm64,windows-2022_x64,windows-2022_x86,windows-11_arm64'
   pull_request:
     paths-ignore:
     - 'versions-manifest.json'
@@ -44,7 +44,7 @@ jobs:
       - name: Generate execution matrix
         id: generate-matrix
         run: |
-          [String[]]$configurations = "${{ inputs.platforms || 'ubuntu-22.04,ubuntu-22.04_arm64,ubuntu-24.04,ubuntu-24.04_arm64,macos-15-intel,macos-14_arm64,windows-2022_x64,windows-2022_x86,windows-11_arm64' }}".Split(",").Trim()
+          [String[]]$configurations = "${{ inputs.platforms || 'ubuntu-22.04,ubuntu-22.04_arm64,ubuntu-24.04,ubuntu-24.04_arm64,rhel-9,rhel-10,macos-15-intel,macos-14_arm64,windows-2022_x64,windows-2022_x86,windows-11_arm64' }}".Split(",").Trim()
           [String[]]$buildModes = "${{ inputs.threading_build_modes || 'default' }}".Split(",").Trim()
           $matrix = @()
           
@@ -55,6 +55,7 @@ jobs:
               $arch = if ($parts[1]) {$parts[1]} else {"x64"}
               switch -wildcard ($os) {
                 "*ubuntu*" { $platform = $os.Replace("ubuntu","linux"); if ($arch -eq "arm64" ) { $os = "${os}-arm" } }
+                "*rhel*" { $platform = $os.Replace("rhel","rhel"); $os = $os.Replace("rhel","setup-actions-rhel") }
                 "*macos*" { $platform = 'darwin' }
                 "*windows*" { $platform = 'win32'; if ($arch -eq "arm64" ) { $os = "${os}-arm" } }
               }
@@ -85,6 +86,14 @@ jobs:
     env:
       ARTIFACT_NAME: python-${{ inputs.VERSION || '3.13.7' }}-${{ matrix.platform }}-${{ matrix.arch }}
     steps:
+      - name: Install prerequisites
+        if: startsWith(matrix.platform, 'rhel')
+        shell: bash
+        run: |
+          RHEL_VERSION=$(rpm -E %rhel)
+          sudo dnf install -y "https://packages.microsoft.com/config/rhel/${RHEL_VERSION}/packages-microsoft-prod.rpm"
+          sudo dnf install -y powershell git
+
       - name: Check out repository code
         uses: actions/checkout@v6
         with:
@@ -112,6 +121,14 @@ jobs:
     env:
       ARTIFACT_NAME: python-${{ inputs.VERSION || '3.13.7' }}-${{ matrix.platform }}-${{ matrix.arch }}
     steps:
+      - name: Install prerequisites
+        if: startsWith(matrix.platform, 'rhel')
+        shell: bash
+        run: |
+          RHEL_VERSION=$(rpm -E %rhel)
+          sudo dnf install -y "https://packages.microsoft.com/config/rhel/${RHEL_VERSION}/packages-microsoft-prod.rpm"
+          sudo dnf install -y powershell git tk sqlite-libs gcc
+
       - name: Check out repository code
         uses: actions/checkout@v6
         with:
diff --git a/builders/build-python.ps1 b/builders/build-python.ps1
index cced69e6..83b9e6aa 100644
--- a/builders/build-python.ps1
+++ b/builders/build-python.ps1
@@ -1,5 +1,6 @@
 using module "./win-python-builder.psm1"
 using module "./ubuntu-python-builder.psm1"
+using module "./rhel-python-builder.psm1"
 using module "./macos-python-builder.psm1"
 
 <#
@@ -58,6 +59,8 @@ function Get-PythonBuilder {
 
     if ($Platform -match 'win32') {
         $builder = [WinPythonBuilder]::New($Version, $Architecture, $Platform)
+    } elseif ($Platform -match 'rhel') {
+        $builder = [RhelPythonBuilder]::New($Version, $Architecture, $Platform)
     } elseif ($Platform -match 'linux') {
         $builder = [UbuntuPythonBuilder]::New($Version, $Architecture, $Platform)
     } elseif ($Platform -match 'darwin') {
diff --git a/builders/rhel-python-builder.psm1 b/builders/rhel-python-builder.psm1
new file mode 100644
index 00000000..19090cd7
--- /dev/null
+++ b/builders/rhel-python-builder.psm1
@@ -0,0 +1,88 @@
+using module "./nix-python-builder.psm1"
+
+class RhelPythonBuilder : NixPythonBuilder {
+    <#
+    .SYNOPSIS
+    RHEL Python builder class.
+
+    .DESCRIPTION
+    Contains methods that required to build RHEL Python artifact from sources. Inherited from base NixPythonBuilder.
+
+    .PARAMETER platform
+    The full name of platform for which Python should be built.
+
+    .PARAMETER version
+    The version of Python that should be built.
+
+    #>
+
+    RhelPythonBuilder(
+        [semver] $version,
+        [string] $architecture,
+        [string] $platform
+    ) : Base($version, $architecture, $platform) { }
+
+    [void] Configure() {
+        <#
+        .SYNOPSIS
+        Execute configure script with required parameters.
+        #>
+
+        $pythonBinariesLocation = $this.GetFullPythonToolcacheLocation()
+
+        ### To build Python with SO we must pass full path to lib folder to the linker
+        $env:LDFLAGS="-Wl,--rpath=${pythonBinariesLocation}/lib"
+        $configureString = "./configure"
+        $configureString += " --prefix=$pythonBinariesLocation"
+        $configureString += " --enable-shared"
+        $configureString += " --enable-optimizations"
+
+        if ($this.IsFreeThreaded()) {
+            if ($this.Version -lt "3.13.0") {
+                Write-Host "Python versions lower than 3.13.0 do not support free threading"
+                exit 1
+            }
+            $configureString += " --disable-gil"
+        }
+
+        ### Compile with support of loadable sqlite extensions.
+        ### Link to documentation (https://docs.python.org/3/library/sqlite3.html#sqlite3.Connection.enable_load_extension)
+        $configureString += " --enable-loadable-sqlite-extensions"
+
+        Write-Host "The passed configure options are: "
+        Write-Host $configureString
+
+        Execute-Command -Command $configureString
+    }
+
+    [void] PrepareEnvironment() {
+        <#
+        .SYNOPSIS
+        Prepare system environment by installing dependencies and required packages.
+        #>
+
+        if ($this.Version -lt "3.9.0") {
+            Write-Host "Python versions lower than 3.9.0 are not supported"
+            exit 1
+        }
+
+        ### Install dependent packages
+        @(
+            "make",
+            "gcc",
+            "gcc-c++",
+            "openssl-devel",
+            "zlib-devel",
+            "bzip2-devel",
+            "sqlite-devel",
+            "ncurses-devel",
+            "readline-devel",
+            "gdbm-devel",
+            "xz-devel",
+            "libffi-devel",
+            "tk-devel"
+        ) | ForEach-Object {
+            Execute-Command -Command "sudo dnf install -y $_"
+        }
+    }
+}
diff --git a/config/python-manifest-config.json b/config/python-manifest-config.json
index 7390b920..3e98f677 100644
--- a/config/python-manifest-config.json
+++ b/config/python-manifest-config.json
@@ -1,7 +1,7 @@
 {
-    "regex": "python-\\d+\\.\\d+\\.\\d+-(\\w+\\.\\d+)?-?(\\w+)-(\\d+\\.\\d+)?-?((x|arm)\\d+(-freethreaded)?)",
+    "regex": "python-\\d+\\.\\d+\\.\\d+-(\\w+\\.\\d+)?-?(\\w+)-(\\d+(\\.\\d+)?)?-?((x|arm)\\d+(-freethreaded)?)",
     "groups": {
-        "arch": 4,
+        "arch": 5,
         "platform": 2,
         "platform_version": 3
     }
diff --git a/tests/ManifestConfig.Tests.ps1 b/tests/ManifestConfig.Tests.ps1
index 5d0ada45..09cb56ef 100644
--- a/tests/ManifestConfig.Tests.ps1
+++ b/tests/ManifestConfig.Tests.ps1
@@ -14,7 +14,11 @@ $stableTestCases = @(
     @{ ReleaseName = "python-3.13.0-linux-20.04-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "linux"; platform_version = "20.04"; arch = "x64-freethreaded"} },
     @{ ReleaseName = "python-3.13.0-linux-22.04-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "linux"; platform_version = "22.04"; arch = "x64-freethreaded"} },
     @{ ReleaseName = "python-3.13.0-win32-x64-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x64-freethreaded"} },
-    @{ ReleaseName = "python-3.13.0-win32-x86-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x86-freethreaded"} }
+    @{ ReleaseName = "python-3.13.0-win32-x86-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x86-freethreaded"} },
+    @{ ReleaseName = "python-3.13.0-rhel-9-x64.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "9"; arch = "x64"} },
+    @{ ReleaseName = "python-3.13.0-rhel-10-x64.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "10"; arch = "x64"} },
+    @{ ReleaseName = "python-3.13.0-rhel-9-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "9"; arch = "x64-freethreaded"} },
+    @{ ReleaseName = "python-3.13.0-rhel-10-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "10"; arch = "x64-freethreaded"} }
 
 ) | ForEach-Object { $_.Configuration = $Configuration; $_ }
 
@@ -29,7 +33,11 @@ $unstableTestCases = @(
     @{ ReleaseName = "python-3.14.0-alpha.5-linux-20.04-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "linux"; platform_version = "20.04"; arch = "x64-freethreaded"} },
     @{ ReleaseName = "python-3.14.0-alpha.5-linux-22.04-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "linux"; platform_version = "22.04"; arch = "x64-freethreaded"} },
     @{ ReleaseName = "python-3.14.0-alpha.5-win32-x64-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x64-freethreaded"} },
-    @{ ReleaseName = "python-3.14.0-alpha.5-win32-x86-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x86-freethreaded"} }
+    @{ ReleaseName = "python-3.14.0-alpha.5-win32-x86-freethreaded.zip"; ExpectedResult = @{ platform = "win32"; platform_version = $null; arch = "x86-freethreaded"} },
+    @{ ReleaseName = "python-3.14.0-alpha.5-rhel-9-x64.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "9"; arch = "x64"} },
+    @{ ReleaseName = "python-3.14.0-alpha.5-rhel-10-x64.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "10"; arch = "x64"} },
+    @{ ReleaseName = "python-3.14.0-alpha.5-rhel-9-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "9"; arch = "x64-freethreaded"} },
+    @{ ReleaseName = "python-3.14.0-alpha.5-rhel-10-x64-freethreaded.tar.gz"; ExpectedResult = @{ platform = "rhel"; platform_version = "10"; arch = "x64-freethreaded"} }
 
 ) | ForEach-Object { $_.Configuration = $Configuration; $_ }
 
diff --git a/tests/python-tests.ps1 b/tests/python-tests.ps1
index 61cfe695..e1dc7a74 100644
--- a/tests/python-tests.ps1
+++ b/tests/python-tests.ps1
@@ -71,7 +71,7 @@ Describe "Tests" {
         "pip uninstall requests -y" | Should -ReturnZeroExitCode
     }
 
-    if (IsNixPlatform $Platform) {
+    if ((IsNixPlatform $Platform) -or ($Platform -match "rhel")) {
 
         It "Check for failed modules in build_output" {
             $buildOutputLocation = Join-Path $env:RUNNER_TEMP "build_output.txt"
diff --git a/tests/sources/python-config-test.py b/tests/sources/python-config-test.py
index cc47ec02..4aaa226f 100644
--- a/tests/sources/python-config-test.py
+++ b/tests/sources/python-config-test.py
@@ -34,7 +34,8 @@
 if pkg_installer:
     expected_lib_dir_path = f'/Library/Frameworks/{framework_name}/Versions/{version_major}.{version_minor}/lib'
 else:
-    expected_lib_dir_path = f'{os.getenv("AGENT_TOOLSDIRECTORY")}/Python/{version}/{architecture}/lib'
+    tools_dir = os.getenv("AGENT_TOOLSDIRECTORY") or os.getenv("RUNNER_TOOL_CACHE")
+    expected_lib_dir_path = f'{tools_dir}/Python/{version}/{architecture}/lib'
 
 # Check modules
 ### Validate libraries path