diff --git a/crates/vm/src/builtins/descriptor.rs b/crates/vm/src/builtins/descriptor.rs
index 55c2275f5bb..e8329fbb572 100644
--- a/crates/vm/src/builtins/descriptor.rs
+++ b/crates/vm/src/builtins/descriptor.rs
@@ -2062,6 +2062,16 @@ impl Callable for PyWrapper {
     flags(DISALLOW_INSTANTIATION)
 )]
 impl Py<PyWrapper> {
+    #[pymethod]
+    fn __reduce__(&self, vm: &VirtualMachine) -> PyResult {
+        let getattr = vm.builtins.get_attr("getattr", vm)?;
+        let args = vm.ctx.new_tuple(vec![
+            self.typ.to_owned().into(),
+            self.name.to_owned().into(),
+        ]);
+        Ok(vm.ctx.new_tuple(vec![getattr, args.into()]).into())
+    }
+
     #[pygetset]
     fn __qualname__(&self) -> String {
         format!("{}.{}", self.typ.name(), self.name)
diff --git a/extra_tests/snippets/stdlib_pickle.py b/extra_tests/snippets/stdlib_pickle.py
index 23d137df43b..855bd79691e 100644
--- a/extra_tests/snippets/stdlib_pickle.py
+++ b/extra_tests/snippets/stdlib_pickle.py
@@ -9,3 +9,7 @@
 assert list(memo) == [1, 7]
 assert memo[1] is left
 assert memo[7] is left
+
+# Slot wrapper descriptors reduce to lookup on their defining class.
+assert object.__str__.__reduce__() == (getattr, (object, "__str__"))
+assert _pickle.loads(_pickle.dumps(object.__str__)) is object.__str__