diff --git a/deeplabcut/gui/tabs/label_frames.py b/deeplabcut/gui/tabs/label_frames.py
index 507f61a00b..4e9e71066b 100644
--- a/deeplabcut/gui/tabs/label_frames.py
+++ b/deeplabcut/gui/tabs/label_frames.py
@@ -8,16 +8,92 @@
 #
 # Licensed under GNU Lesser General Public License v3.0
 #
+from __future__ import annotations
+
 import os
+from pathlib import Path
+
 from PySide6 import QtWidgets
 from PySide6.QtCore import Qt
+
 from deeplabcut.generate_training_dataset import check_labels
 from deeplabcut.gui.components import DefaultTab
 from deeplabcut.gui.widgets import launch_napari
 
 
-def label_frames(config_path):
-    _ = launch_napari(config_path)
+def label_frames(
+    config_path: str | Path | None = None,
+    image_folder: str | None = None
+):
+    """Launches the napari-deeplabcut labelling GUI.
+
+    For more information on labelling data with napari-deeplabcut, see our docs:
+        https://github.com/DeepLabCut/napari-deeplabcut?tab=readme-ov-file#usage
+
+    If no parameters are given, the napari-deeplabcut labelling GUI is simply open,
+    and the folder containing the images to label can be dropped into the GUI.
+
+    If the `config_path` and the `image_folder` are given as arguments, the given
+    `image_folder` for the project is opened in the napari-deeplabcut GUI to be labeled.
+    If only the `config_path` is given, the first image folder is opened.
+
+    Parameters
+    ----------
+    config_path: str, Path, None
+        Full path of the project config.yaml file.
+
+    image_folder: str, None
+        Name of the image folder to open for labelling.
+
+    Examples
+    --------
+    Opening the napari-deeplabcut annotation GUI without opening a specific folder of
+    images to label. You then need to drag-and-drop your image folder into the GUI.
+    See the napari-deeplabcut docs linked above for more infomation about labelling in
+    napari-deeplabcut.
+    >>> import deeplabcut
+    >>> deeplabcut.label_frames()
+
+    Opening the images extracted from the "2025-01-01-experiment7" video in
+    napari-deeplabcut on Windows. The project's folder structure should look as follows:
+    reaching-task/                    # project root directory
+    ├── config.yaml                   # project configuration file
+    └── labeled-data/                 # folder containing all extracted image folders
+        ├── ...
+        ├── 2025-01-01-experiment7    # folder containing the images to label
+        └── ...
+    >>> deeplabcut.label_frames(
+    >>>     "C:\\myproject\\reaching-task\\config.yaml",
+    >>>     "2025-01-01-experiment7",
+    >>> )
+
+    Opening the images extracted from the first video listed in the project
+    configuration in napari-deeplabcut on a Unix system.
+    >>> deeplabcut.label_frames("/users/john/project/config.yaml")
+    """
+    files = None
+    if config_path is None:
+        if image_folder is not None:
+            raise ValueError(
+                f"If the ``config_path`` is None, the ``image_folder`` must be None "
+                f"too. Found {image_folder}. To label the images in {image_folder}, "
+                f"give the project configuration file as `config_path`."
+            )
+    else:
+        data_dir = Path(config_path).parent / "labeled-data"
+        if image_folder is None:
+            image_dirs = [path for path in data_dir.iterdir() if path.is_dir()]
+            if len(image_dirs) == 0:
+                raise ValueError(
+                    f"Could not find any image folders in {data_dir}. Please check "
+                    f"the config path given to `deeplabcut.label_frames(...)`"
+                )
+            image_dir = list(sorted(image_dirs))[0]
+        else:
+            image_dir = data_dir / image_folder
+
+        files = [str(image_dir), str(config_path)]
+    _ = launch_napari(files=files)
 
 
 refine_labels = label_frames